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Glycomet is an oral diabetes medicine used to treat type 2 of diabetes. Its active substance is Metformin which belongs to biguanide class of substances. It reduces concentration of glucose in blood suppressing metabolism of glucose in the liver, reducing absorption of glucose from the gastrointestinal tract, and enhancing its utilization in tissues. Glycomet stabilizes or reduces body weight. The therapeutic effect is not observed in the absence of insulin in the blood. It does not cause hypoglycemic reactions. It improves fibrinolytic properties of blood. It I used to treat diabetes mellitus (type 2) in adults also in patients for who treatment with sulfonylurea was ineffective, especially in cases followed by obesity.
Do not take if this medication was not prescribed to you and do not exceed the recommended dose. Take it with a meal if your doctor did not recommend you to take it differently. Glycomet is administered for taking twice daily by 500 mg or 850 mg once daily to treat type 2 diabetes in adults. Basing on the glucose levels in the blood the dose of Glycomet can be increased to the maximum daily dose of 2550 mg given in three divided doses.This medication is able to cause a life threatening condition in some people which is characterized by weakness, increasing sleepiness, slow heartbeat, cold feeling, muscle pain, abdominal pain, shortness of breath, feeling light-headed, and fainting. It is called lactic acidosis.
If you experience such symptoms get immediate medical attention. Also be attentive to symptoms of low blood sugar which include hunger, confusion, irritability, drowsiness, headache, weakness, fast heartbeat, tremors, sweating, seizure and have a source of sugar at hand always.
Avoid drinking alcohol. Hypersensitivity, hyperglycemic coma, ketoacidosis, kidney failure, liver disease, heart failure, acute myocardial infarction, respiratory failure, dehydration, infectious diseases, extensive surgery and trauma, alcoholism, reduced-calorie diet (less than 1000 kcal/day), lactic acidosis (including history), pregnancy, breastfeeding. The drug is not prescribed to take 2 days before a surgery, radioisotope and X-ray examinations, CAT scanning (CT).
Glycomet is contraindicated in patients over 60 y.o., or doing hard physical work (risk of lactic acidosis increases).Cimetidine (Tagamet) increases blood levels of Glycomet affecting its metabolism. Glycomet is not compatible with alcohol. Concomitant administration with indirect anticoagulants and Cimetidine should be done with cautiousness. Glycomet enhances metabolism of Furosemide. Derivatives of sulfonylurea, insulin, acarbose, inhibitors of MAO, oxytetracycline, cyclophosphamide and salicylates increase the effects of Glycomet. Decrease of hypoglycemic effect of Glycomet is caused by co-administration with thyroid medicines, birth control pills and other hormones, Epinephrine, Glucagon, thiazide diuretics, nicotinic acid derivates.
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