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Levitra is an oral drug used to treat erectile dysfunction. Sexual stimulation causes the production and release of nitric oxide from the nerves endings of the cavernous bodies of the penis hereby activating enzyme guanylate cyclase.
Guanylate cyclase in its turn is responsible for production of cyclic guanosine monophosphate (cGMP). The cGMP causes widening and relaxation of the blood vessels carrying blood to the penis. Levitra prevents phosphodiesterase-5 enzyme from destroying cGMP and thus helps to support blood flow to the penis.
Levitra has not been studied in people with cardiovascular disease, so it is preferable to avoid Levitra if in patients who have a stroke or heart failure, or a heart attack in history and especially within last six month.
Before to take Levitra inform your doctor if you have kidney or liver problems, a bleeding disorder, stomach ulcer, or an inherited retinal disorder such as retinitis pigmentosa, allergic reaction to this medicine or any other medicines, deformation of the penis such as angulation, cavernous fibrosis (Peyronie's disease), as well as in diseases that contribute to the development of priapism (sickle-cell anemia, multiple myeloma, leukemia, or leukemia).
Levitra is contraindicated in patients with hypersensitivity to its ingredients, ones treated with organic nitrates, in patients under 16 y.o., or those who take HIV protease inhibitors such as indinavir and ritonavir.
Levitra is usually well tolerated and side effects if occur are transient.
The most frequent side effects are: headache, flushing (hyperemia of the person); frequent; dizziness, diarrhea phenomenon, nausea, nasal congestion.
More rare and uncommon adverse effects are photosensitivity of skin, hypertension, back pain, watery eyes, hypotension, myalgia, priapism.
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