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Dramamine is used to treat sea and air sickness, Meniere's disease, to prevent and treat symptoms of vestibular and labyrinth disorders (dizziness, nausea, vomiting, except for symptoms caused by anticancer chemotherapy).
Active substance of the drug is Dimenhydrinate, it blocks histamine H1-receptors and m-cholinergic receptors of central nervous system, inhibits hyperstimulated functioning of the labyrinth.
Dramamine reduces dizziness, has antiemetic, anti-vomiting, sedative, and mild anti-allergic effect. The results of its action are manifested in 20-30 minutes and continue for 4-6 hours.To prevent sea or air sickness take Dramamine at least 30 minutes before the planned trip.
Adults and adolescents under 14 years of age should take 50-100 mg, children between 2-6 years of age should take 25-50 mg, and children between 7-14 years should take 50 mg dose of Dramamine. For vestibular disorders adults should take 50-100 mg (each for hours if necessary) but not more than 400 mg a day; for children reduction of the dose is needed. Take exactly as prescribed by your doctor.
Take with a full glass of water.This medicine may change your ability to concentrate attention, to drive, and operate machinery. Be especially cautious performing any hazardous activities or refuse from doing it due to possible dizziness, drowsiness, or blurred vision caused by Dramamine. Limit intake of alcoholic beverages as it increases drowsiness and dizziness while you are taking dimenhydrinate.
Besides possible allergic reaction (facial swelling, hives, rash) Dramamine may cause drowsiness or dizziness, restlessness, tiredness, insomnia, inability to concentrate attention, excitation, nervousness, or insomnia, blurred or double vision, weakness of night and color vision, accommodation disorders, dry mouth, nose, or throat, decreased appetite, nausea, vomiting, or diarrhea, difficulty urinating, or an irregular or fast heartbeat. If you experience side effects listed above and they become bothersome inform your doctor about it.
Dramamine enhances the effects of atropine, tricyclic antidepressants, catecholamines, barbiturates, alcohol, sedatives and hypnotics, neuroleptics, weakens - corticosteroids, anticoagulants. Response to apomorphine is diminised by Dramamine.
Dimenhydrinate also reduces depressive effect of acetylcholine on the heart muscle. Concomitant use of Dramamine with bismuth, scopolamine, anesthetics and psychotropic drugs make vision disorders more likely to occur. Dramamine is incompatible with ototoxic antibiotics (viomitsin, amikacin, streptomycin, neomycin, kanamycin) and may cause the development of irreversible hearing loss.
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