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Description
Isordil is used for the treatment and prevention of angina caused by coronary artery disease because angina occurs when the heart muscle does not get enough blood.
This medication is used before physical activities (exercise, sexual activity). Isordil belongs to a class of drugs called nitrates. This drug helps to relax and widen blood vessels and after taking Isordil blood can flow more easily to the heart.
The usual initial dose of Isordil is 5 mg to 20 mg, two or three times daily. For maintenance therapy it may be between 10 mg and 40 mg, two or three times per day is recommended. Some patients may require higher doses but it depends on their therapy and conditions.
To minimize tolerance you need a daily dose-free interval of at least 14 hours. The optimal interval can be different because of the individual patient, dose and regimen. Sit down before using this medication. Isordil should be taken by mouth with a glass of water without food. It should be dissolved under the tongue and should not be crushed or chewed.
Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food. Take your medicine regularly. Do not take your medicine more often than directed, bigger dose that it needs and for longer period of time. Do not stop taking this medicine suddenly. In this way your symptoms may get worse.
Firstly ask your doctor or health care professional.Severe hypotension, particularly with upright posture, may be caused by even small doses of Isordil. The patients who have hypertension, who may be volume depleted should take this drug with caution. Hypotension caused by Isordil may come together with paradoxical bradycardia and increased angina pectoris.
Your doctor needs to know if you have previous heart attack or heart failure, an unusual or allergic reaction to isosorbide dinitrate, nitrates, other medicines, foods, dyes, or preservatives, you pregnant or trying to get pregnant or you are breast-feeding.
If you take Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) together with Isordil it can increase the blood pressure lowering effects and may cause excessive blood pressure reduction.
Do not take this medicine if you also take medicines used to treat erectile dysfunction (ED) like sildenafil, tadalafil, and vardenafil, medicines for high blood pressure, other medicines for angina or heart failure.
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