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Our customers provided by all information about the products all time. Main component of antiviral drug Rebetol is Ribavirin. It is used in combination with interferon drugs Intron A or PEG-Intron to treat chronic hepatitis C. Rebetol inhibits the replication of new virions, selectively inhibits synthesis of viral RNA, it does not suppress synthesis of RNA in a normal cells.
Rebetol is the most effective against: herpes simplex virus, virus of smallpox, influenza viruses A and B, paramyxovirus (parainfluenza, mumps, Newcastle disease), reovirus, oncogenic RNA viruses. Rebetol is contraindicated in patients hypersensitive to the components of Rebetol, in pregnant and breastfeedign women, in patients with chronic heart failure, myocardial infarction, kidney or liver failure, severe anemia, decompensated cirrhosis, autoimmune diseases, incurable thyroid disease, severe depression with suicidal intentions, children and adolescents under 18.
Cautiousness should be exercised in patients with decompensated diabetes mellitus, pulmonary embolism, heart failure, thyroid disease (including hyperthyroidism), impaired clotting, thrombophlebitis, myelosuppression, haemoglobinopathy (thalassemia, sickle cell anemia), depression, suicidality (also in history).
Concomitant use with other antiviral drugs such as zidovudine (Retrovir), zalcitabine (Hivid) or stavudine (Zerit), may cause lactic acidosis. Medications which contain Mg2+ É Al3+, and also simethicone decrease absorption of Retrovir. Retrovir suppresses effects of zidovudine.
In the patients with HIV infection concomitant treatment with Retrovir, zidovudine and stavudine leads to HIV viremia (a condition where viruses get into the bloodstream and can affect the rest of the body) and requires change of treatment.
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