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Keflex is attributed as antibiotic of cephalosporins group which act against bacteria preventing formation of their cell walls. It is enough resistant to penicillinases of gram positive microorganims but can be destroyed by beta-lactamases of gram negative ones. It shows broad spectrum activity against gram positive microogranisms such as
- Staphylococcus, Staphylococcus epidermidis
- Corynebacterium diphtheriae
- Actinomyces israelii
- Bacillus antracis
- gram negative microorganisms like Escherichia coli
- Proteus mirabilis
- Neisseria gonorrhoeae
- Neisseria meningitidis,
Common infections that are treated with Keflex include infections of the middle ear, tonsils, throat, larynx (laryngitis), bronchi (bronchitis) and pneumonia as well as in urinary tract, skin, and bones. Before using Keflex, tell your doctor if you are allergic to any drugs (especially penicillins), have kidney or liver disease, a stomach or intestinal disorder such as colitis, and diabetes. Hypersensitivity to Keflex, cephalosporins (Ceclor, Duricef, Omnicef, Spectracef, Suprax, Cefzil, Fortaz, Ceftin) and beta-lactamase antibiotics. Cautiousness should be exercised in patients with kidney disorder, pseudomembranous colitis, pregnancy, breastfeeding and babies younger than 6 month.
Most common side effects may include signs of allergy (hives, rash, swelling of face and tongue), seizure, fever, sore throat, and headache with a severe blistering, peeling, and red skin rash, pale or yellowed skin, dark colored urine, fever, hallucinations, confusion or weakness, easy bruising or bleeding, unusual weakness, confusion, agitation, decreased or absent urination. In case of serious and persistent side effects listed above seek for immediate medical help.
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