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Combivent contains two active substances: ipratropium bromide (Atrovent) and Levosalbutamol. Ipratropium blocks m-cholinoreceptors of smooth muscles in the bronchi and treacheas, suppresses reflect constriction of bronchis, decreases secretion of the mucous membrane in the respiratory tract.

The drug is used in treatment of chronic obstructive pulmonary disease with spasm of the airways. Effect of bronchodilators consists in dilatation and enlargement of the airways by relaxing the muscles of respiratory tract. Ipatropium works different way, it has a structural similarity with acetylcholine and becomes its competitive antagonist. The medication effectively prevents spasm of the bronchi due to breathing with cigarette smoke, cold air, activity of different agents which cause spasm of bronchi associated with influence of n.vagus.

Cautiousness should be exercised in individuals with

  • close-angle glaucoma
  • urinary tract obstruction (prostatic hypertrophy)
  • problems with urination
  • coronary artery disease
  • hypertension
  • heart failure
  • tachyarrhythmia
  • epileptic syndrome
  • hyperthyroidism
  • diabetes mellitus
  • hypokalemia
  • liver or kidney failure
  • pregnancy and breastfeeding women.

Safety of Combivent has not be studied in children. Cautiousness should be exercised in individuals with close-angle glaucoma, urinary tract obstruction (prostatic hypertrophy), problems with urination, coronary artery disease, hypertension, heart failure, tachyarrhythmia, epileptic syndrome, hyperthyroidism, diabetes mellitus, hypokalemia, liver or kidney failure, pregnancy, breastfeeding women.

Inform your doctor about all medications and herbal products you are taking and especially about

  • atropine (Donnatal, and others)
  • belladonna preparations
  • clidinium (Quarzan)
  • mepenzolate (Cantil)
  • glycopyrrolate (Robinul)
  • methantheline (Provocholine)
  • hyoscyamine (Anaspaz, Cystospaz, Levsin, and others)
  • dicyclomine (Bentyl)
  • propantheline (Pro-Banthine)
  • propantheline (Pro-Banthine)
  • methscopolamine (Pamine)
  • scopolamine (Transderm-Scop)
  • methscopolamine (Pamine)
  • scopolamine (Transderm-Scop)
  • a beta-blocker such as carvedilol (Coreg)
  • atenolol (Tenormin, Tenoretic)
  • metoprolol (Lopressor)
  • propranolol (Inderal)
  • methscopolamine (Pamine)
  • scopolamine (Transderm-Scop)
  • diuretics
  • diet pills
  • a stimulant
  • ADHD medication
  • over-the-counter cold or allergy medicines,
  • an MAO inhibitor such as phenelzine (Nardil)
  • isocarboxazid (Marplan)
  • rasagiline (Azilect)
  • selegiline (Eldepryl, Emsam)
  • tranylcypromine (Parnate)

Explore the following products in this category: PROAIR INHALER and THEO-24 CR

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