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Asacol is an anti-inflammatory drug which acts on the lining of the gut to reduce inflammation tissue damage, and diarrhea and treat ulcerative colitis, proctosigmoiditis, and proctitis. Asacol becomes active in the small intestine just before the large intestine.
This drug may be also good in treatment of patients with Crohn's disease which affects also the small bowel. Asacol contains active component mesalamine, an anti-inflammatory drug, which is released from covering only when ðÍ>7, and olsalazine (5-aminosalicylic acid dimer) which is also active in distal segments of gastrointestinal tract.
Consult with your doctor about necessary dosage before to start treatment. Do not use in larger quantities than prescribed. Take Asacol orally with a meal or a glass of milk. Swallow the whole pill with water.
Do not break, crush or chew the tablets before to swallow them.
Recommended daily dose for treatment of moderately active ulcerative colitis is 4.8g divided in three intakes; treatment contiues 6 weeks in adults. Lower doses are required to treat mild acute exacerbations of ulcerative colitis in adults: daily dose of 2.4g should be taken as divided doses.
Maintenance of remission of ulcerative colitis and Crohn's ileocolitis: take up to 2.4g a day in divided doses. On impairment of renal function dosage should be adjusted. This medication is not recommended to use in children.
Asacol is not recommended in patients with renal impairment and caution should be exercised in patients with raised blood urea or proteinuria. Use with caution in adult patients having a normal renal function. If renal failure develops in patients treated with Asacol it can be caused by mesalazine-induced nephrotoxicity.
Phenergan should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Possible adverse effects to the infant may exclude breast-feeding.
Consult your doctor if you need to breastfeed your baby.
Inform your doctor if you are taking the following drugs: azathioprine (Imuran) or mercaptopurine (Purinethol); pentamidine (Nebupent, Pentam); tacrolimus (Prograf); rifampin (Rifadin, Rimactane, Rifater), amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet), capreomycin (Capastat), vancomycin (Vancocin, Vancoled), adefovir (Hepsera), acyclovir (Zovirax), cidofovir (Vistide), or foscarnet (Foscavir), aldesleukin (Proleukin), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), carmustine (BiCNU, Gliadel), plicamycin (Mithracin), streptozocin (Zanosar), or tretinoin (Vesanoid); aspirin and other NSAIDs such as diclofenac (Voltaren), ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), ketorolac (Toradol), etodolac (Lodine), diflunisal (Dolobid), flurbiprofen (Ansaid), mefenamic acid (Ponstel), indomethacin (Indocin), ketoprofen (Orudis).
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